Patrick Dolan

This study uses scRNA-seq to analyze EV-D68 infection in human spinal cord organoids, revealing strain-specific tropism and host transcriptional responses associated with AFM.

This study shows that activating FcγRs on monocytes are necessary for optimal Mayaro virus clearance and prevent monocytes from being infected.

This study shows that neural stem cell differentiation rewires the chaperone network, reducing TRiC/CCT and increasing sHSPs, which shifts proteostasis strategy and may contribute to neurodegenerative disease susceptibility.

The paper characterizes an antiviral immunity pathway in mosquitoes that uses endogenous viral elements for long-term protection and self-nonself discrimination.

The paper characterizes the genomic structure and function of endogenous viral elements (EVEs) in the Aedes aegypti Aag2 cell line using long-read sequencing, revealing their role in antiviral immunity.