Mohak Sharda

This paper investigates how DNA binding proteins evolved sequence specificity by analyzing the IHF/HU family and reconstructing ancestral sequences.

The paper introduces a method to improve sequencing quality for amplicon libraries by using N spacers in primers, eliminating the need for PhiX spike-in and enabling multiplexing.

This study investigates the evolutionary distribution of bacterial non-homologous end joining (NHEJ) through comparative genomics and phylogenetic analysis across 6000 genomes, finding it is sporadic and correlated with genome size and growth rate.

The paper introduces CoVa, a Python-based tool for analyzing SARS-CoV-2 genomes, identifying selection signatures, and defining sequence typing, with findings on geographic variation and mutation rates.