Author

Darcie D. Seachrist

Case Western Reserve UniversityORCID 0000-0001-8399-3391Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Ruth A. KeriiD· 2 shared Adrian V. LeeiD· 1 shared Alexander Chih-Chieh ChangiD· 1 shared Berfin DinciD· 1 shared Christopher MerkeliD· 1 shared Creg J. WorkmaniD· 1 shared Daisong Liu· 1 shared Dario A.A. VignaliiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Ruth A. KeriORCID

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Author profile →

2 papers

Recent·Most cited

Integrated Collagen Architecture and Composition Improve Risk Stratification in Triple-Negative Breast Cancer

Resul Özbilgiç, Berfin Dinc, Kavya Vipparthi, Darcie D. Seachrist, Marlo M. Nicolas, Ruth A. Keri, Xuefeng Liu, Murat Yıldırım, Mihriban Karaayvaz

This paper identifies collagen architecture and composition as prognostic biomarkers in triple-negative breast cancer, improving risk stratification beyond standard clinicopathologic features.

Neoplasia · Sep 12, 2026Peer-reviewedCancer Biology

Novel transplantable mouse cell line model recapitulates invasive lobular breast carcinoma (ILC) phenotype and immune microenvironment.

Sayali Onkar, Daisong Liu, Darcie D. Seachrist, Jian Zou, Christopher Merkel, Insa Thale, Alexander Chih-Chieh Chang, Linda R. Klei, Jian Chen, Kristen L. Weber-Bonk, Kai Ding, Laura Savariau, Megan E. Yates, Jagmohan Hooda, Laura P. Stabile, , Steffi Oesterreich

The paper develops a novel mouse cell line model of invasive lobular breast carcinoma that recapitulates human tumor phenotype and immune microenvironment, offering a preclinical platform for therapy evaluation.

bioRxiv · Jul 31, 2026 · PreprintCancer Biology