Author

Albert M. Isaacs

Nationwide Children's HospitalORCID 0000-0001-8405-2454Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:scATAC-seq· 1 Assay:scRNA-seq· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Aaron VargheseiD· 1 shared Adithe RivaldiiD· 1 shared Alex Handler WagneriD· 1 shared Andrew T. HaleiD· 1 shared Benjamin D. SunkeliD· 1 shared Benjamin KellyiD· 1 shared Cole A. HarringtoniD· 1 shared Elaine R. MardisiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Aaron VargheseORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicineNeurosurgeryPeer-reviewedNov 12, 2025

Genetically determined alterations in inflammation and infection-associated genes are associated with hydrocephalus in patients of African Ancestry

Andrew T. Hale, Jing He, Gregory M. Larkin…·Albert M. Isaacs

The paper identifies TMEM208 as a transcriptome-wide predictor of hydrocephalus in African ancestry patients, linking it to inflammation and infection pathways.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintSep 21, 2025

PEDIA-BRAIN: A single nuclei multiomic encyclopedia of the human pons provides a resource for normal development and disease vulnerability

Tianli Ding, Gary Schweickart, Kaitlin Kaiser…·Michelle Ariana Wedemeyer

PEDIA-BRAIN provides a single nuclei multiomic resource of the human pons across development, revealing oligodendrocyte maturation trajectories and disease-related perturbations in DMG and MS.

DOI 10.1101/2025.09.21.677597

humanscRNA-seq

𝕏 PostBluesky