Meng Law

This study examines sex differences in structural brain alterations in common epilepsies using neuroimaging data from a large international cohort, finding some regional differences but no significant sex-by-diagnosis interactions.

The paper uses factor analysis on multimodal biomarkers to identify latent constructs of brain health, finding five distinct constructs associated with age and cognitive function.

This study examines relationships between MRI-based measures of neurovascular integrity and fluid transport in older adults, finding age-related changes and stable inter-relationships among these metrics.

This study finds plasma pTau-217 correlates with cognition and brain atrophy in cognitively healthy older adults and strongly correlates with its CSF counterpart.

The paper compares four automated MRI segmentation methods for epilepsy resection cavities to manual segmentation, finding SPM-based methods outperform deep learning approaches in most cases.

This study identifies divergent patterns of atypical cortical asymmetry and regional atrophy in temporal lobe epilepsy using MRI data from a large multi-site cohort.

The paper analyzes cerebral perivascular spaces (PVS) in healthy individuals to establish normal ranges and identifies factors like BMI, time of day, and genetics that influence PVS volume and distribution.

This paper introduces an image processing method to enhance perivascular space visibility and quantification using MRI by combining T1- and T2-weighted images with adaptive filtering.

This study finds smaller limbic brain volumes are associated with greater immunosuppression in HIV+ adults across five continents.

This paper shows that perivascular space fluid affects diffusion tensor imaging metrics in white matter, challenging previous interpretations of DTI findings.