Giuseppe Barisano

The paper identifies progranulin as a mediator of immune suppressive niches in brain metastasis using cross-species spatial transcriptomics and functional analyses.

CSF-Seq profiles cerebrospinal fluid transcriptomes to identify a prognostic gene signature for leptomeningeal disease.

This study examines how biological sex and BMI affect the longitudinal changes in MRI-visible perivascular spaces (MV-PVS) in adolescents and young adults.

This study examines the relationship between sleep, walking, and cognition in Parkinson's disease, finding that walking difficulties directly impact cognition, while PVS does not mediate these associations.

This study examines the effects of one-night partial sleep deprivation on perivascular space volume fraction using the Stockholm Sleepy Brain Study, finding no significant overall association but some interactions that did not survive multiple comparisons.

This study identifies molecular signatures of brain mimicry and adaptation in breast cancer brain metastases using spatial transcriptomic profiling and a new algorithm called Equivalent Expression Index.

This study finds that smaller ipsilesional hippocampal volume is associated with worse upper limb sensorimotor impairment in chronic stroke patients, with a stronger effect in women.

This study shows that global brain health, measured by brain age, influences post-stroke sensorimotor outcomes and mediates the effect of lesion damage.

This study finds that smaller spared subcortical nuclei are linked to worse sensorimotor outcomes after stroke, varying by time since stroke and type of impairment.

The paper shows that early cognitive dysfunction is associated with altered perivascular space presence and distribution, linked to tau tangle deposition in Alzheimer's disease pathology.

The paper analyzes cerebral perivascular spaces (PVS) in healthy individuals to establish normal ranges and identifies factors like BMI, time of day, and genetics that influence PVS volume and distribution.

This paper introduces an image processing method to enhance perivascular space visibility and quantification using MRI by combining T1- and T2-weighted images with adaptive filtering.

This paper shows that perivascular space fluid affects diffusion tensor imaging metrics in white matter, challenging previous interpretations of DTI findings.