Author

Ryan L. Beckner

The University of Texas Southwestern Medical CenterORCID 0000-0001-8425-630XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

G. P. LiszczakiD· 2 shared Abby WalterscheidiD· 1 shared Benjamin R. KrogeriD· 1 shared Catherine ValadeziD· 1 shared Christien Carter· 1 shared Lily KimiD· 1 shared Michael McConvilleiD· 1 shared Stephen S. ChungiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

G. P. LiszczakORCID

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2 papers

Recent·Most cited

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedMay 6, 2026

Chiral inversion mutagenesis identifies geometrically constrained residues within self-associating low-complexity domains

Ryan L. Beckner, Lily Kim, Christien Carter…·Glen Liszczak

The paper uses chiral inversion mutagenesis to identify geometrically constrained residues in LCDs that affect self-association.

DOI 10.1073/pnas.2535888123

protein structureexperimental assay

𝕏 PostBluesky

BiochemistryScience AdvancesPeer-reviewedApr 16, 2025

Enigmatic missense mutations can cause disease via creation of de novo nuclear export signals

Michael McConville, Toby Thomas, Ryan L. Beckner…·G. P. Liszczak

The paper identifies missense mutations that create nuclear export signals, leading to disease, and shows therapeutic strategies can restore function.

4 citations

𝕏 PostBluesky