Author

Patrícia P. Coltri

Universidade de São PauloORCID 0000-0001-8447-7516Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:E. coli· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:statistical model· 1 Organism:yeast· 1

Frequent Co-Authors

Alma L. BurlingameiD· 1 shared Andrew J. MacRaeiD· 1 shared Eva Hrabeta‐RobinsoniD· 1 shared Mathias Mistretta PiresiD· 1 shared Maurício CantoriD· 1 shared Melissa S. JuricaiD· 1 shared Paulo R. GuimarãesiD· 1 shared Robert J. ChalkleyiD· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 13 mutual co-author links

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1 shared paperMolecular Biology

Alma L. BurlingameORCID

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2 papers

Recent·Most cited

A two-step probing method to compare lysine accessibility across macromolecular complex conformations

Andrew J. MacRae, Patrícia P. Coltri, Eva Hrabeta‐Robinson, Robert J. Chalkley, Alma L. Burlingame, Melissa S. Jurica

The paper introduces a two-step chemical probing method using tandem mass-spectrometry to assess lysine reactivity in macromolecular complexes, showing it reflects structural models of ribosomes and spliceosomes.

RNA Biology · Jun 19, 2019Peer-reviewedMolecular Biology

Interaction paths promote spliceosome module integration and network-level robustness to cascading effects

Paulo R. Guimarães, Mathias Mistretta Pires, Maurício Cantor, Patrícia P. Coltri

The paper uses spectral graph theory to analyze the spliceosome network's fragility to cascading effects, showing modular path concentration promotes robustness but may increase subunit vulnerability.

Scientific Reports · Nov 22, 2018Peer-reviewedMolecular Biology