Eva Hrabeta‐Robinson

The paper introduces SMAdd-seq, a method to profile chromatin accessibility using small molecule intercalation and nanopore sequencing, and demonstrates its application in yeast.

This study shows U2AF1S34F enhances lung cell tumorigenicity when combined with KRAS mutations and environmental stress, altering splicing and stress responses.

The paper develops FLAIR2 to detect haplotype-specific transcript variation using long-read sequencing, revealing ADAR's role in splicing and RNA editing in lung cancer.

DeepSea is a deep learning model for segmenting and tracking single cells in time-lapse microscopy images, showing cell size control in embryonic stem cells during G1 phase.

The paper uses nanopore sequencing to analyze full-length transcripts in CLL samples with and without SF3B1 mutations, revealing altered intron retention and splicing patterns.

The paper uses long-read sequencing to identify U2AF1 S34F mutation-induced isoform changes in lung cancer, revealing novel transcripts and functional consequences.

The paper introduces a two-step chemical probing method using tandem mass-spectrometry to assess lysine reactivity in macromolecular complexes, showing it reflects structural models of ribosomes and spliceosomes.