Author

Jae Seok Yoon

Cystic Fibrosis FoundationORCID 0000-0001-8460-3455Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam L. Mackey· 1 shared Alfredo Perales‐PuchaltiD· 1 shared Andrey SivachenkoiD· 1 shared C. Macadino· 1 shared Calvin U. Cotton· 1 shared Christopher A. AherniD· 1 shared Daniel T. InfieldiD· 1 shared David B. WeineriD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Adam L. Mackey

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintJul 1, 2024

Upregulation of a nonsense mediated decay (NMD) insensitive CFTR mRNA isoform has therapeutic potential for the treatment of 3 Prime CFTR PTC variants

Norm Allaire, M. Armstrong, Jae Seok Yoon…·Calvin U. Cotton

The paper shows that upregulating an NMD-insensitive CFTR mRNA isoform with ASOs and ETI can restore partial Cl- transport function in cells with 3' PTC mutations.

1 citation

humanbulk RNA-seq

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Molecular BiologyNature CommunicationsPeer-reviewedFeb 18, 2019

Engineered transfer RNAs for suppression of premature termination codons

John D. Lueck, Jae Seok Yoon, Alfredo Perales‐Puchalt…·Christopher A. Ahern

This paper identifies engineered transfer RNAs (ACE-tRNA) that suppress premature termination codons in mammalian cells and mice, showing high suppression activity for common disease-causing nonsense codons.

159 citationstop 3%

humanmouse

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