Author

Daniel Muñoz-Reyes

Consejo Superior de Investigaciones CientíficasORCID 0000-0001-8464-1996Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alicia MansillaiD· 2 shared Celia Miró-Rodríguez· 2 shared María José Sánchez-BarrenaiD· 2 shared Sara Pérez-Suárez· 2 shared Carlos Requena-TrigueroiD· 1 shared Charlie W. E. Tomlinson· 1 shared D. FearoniD· 1 shared Eda ÇapkıniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBiochemistry

Alicia MansillaORCID

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2 papers

Recent·Most cited

BiochemistryJournal of Medicinal ChemistryPeer-reviewedNov 10, 2025

FDA drug repurposing uncovers modulators of dopamine D2 receptor localization via disruption of the NCS-1 interaction

Daniel Muñoz-Reyes, Lorena Aguado, Sandra Arroyo‐Urea…·María José Sánchez-Barrena

The paper identifies FDA-approved drugs that disrupt the NCS-1/D2R interaction, modulating D2R localization without affecting its signaling.

3 citations

humanproteomics

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BiophysicsbioRxivPreprintJun 18, 2025

Combining crystallographic fragment screening, algorithmic merging and digitized chemical synthesis efficiently yields scaffolds that target diverse NCS-1 protein-protein interactions implicated in neurological disorders

Daniel Muñoz-Reyes, Kate K. Fieseler, Max Winokan…·María José Sánchez-Barrena

This paper combines crystallographic fragment screening, algorithmic merging, and automated synthesis to generate scaffolds targeting NCS-1 PPIs involved in neurological disorders.

1 citation

protein structureexperimental assay

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