Author

Brittany Intzandt

Sunnybrook Research InstituteORCID 0000-0001-8475-988XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 8 Approach:statistical model· 7 Assay:imaging· 6 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Claudine Joëlle GauthieriD· 8 shared Dalia Sabra· 7 shared Louis BhereriD· 7 shared Zacharie Potvin-JutrasiD· 6 shared Ali RezaeiiD· 5 shared Amélie Mainville-Berthiaume· 5 shared Anil NigamiD· 5 shared Christine GagnoniD· 5 shared

Activity by Year

2018-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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8 shared papersNeuroscience

Claudine Joëlle GauthierORCID

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Regional distribution of white matter hyperintensity burden in coronary artery disease and links with coronary revascularization procedure

Zacharie Potvin-Jutras, Stefanie A Tremblay, Ali Rezaei, Safa Sanami, Dalia Sabra, Brittany Intzandt, Lindsay Wright, Christine Gagnon, Amélie Mainville-Berthiaume, Olivier Parent, Mahsa Dadar, Josep Iglesies‐Grau, Christopher J. Steele, Mathieu Gayda, Anil Nigam, , Claudine Joëlle Gauthier

This study examines regional white matter hyperintensity (WMH) burden in coronary artery disease (CAD) and finds that CAD is associated with higher WMH volumes, with CABG linked to greater superficial WMH burden than PCI.

bioRxiv · May 15, 2026 · PreprintNeuroscience

Greater cardiorespiratory fitness is associated with higher cerebral blood flow and lower oxygen extraction fraction in healthy older adults

Safa Sanami, Ali Rezaei, Stefanie A Tremblay, Zacharie Potvin-Jutras, Dalia Sabra, Brittany Intzandt, Christine Gagnon, Amélie Mainville-Berthiaume, Lindsay Wright, Mathieu Gayda, Josep Iglesies‐Grau, Anil Nigam, Louis Bherer, Claudine Joëlle Gauthier

This study finds that higher cardiorespiratory fitness in older adults is linked to increased cerebral blood flow and decreased oxygen extraction fraction.

Journal of Cerebral Blood Flow & Metabolism · Jan 16, 2026Peer-reviewedBiophysics

Preservation of cerebral vascular and metabolic health with greater cardiorespiratory fitness in coronary artery disease

Safa Sanami, Stefanie A Tremblay, Zacharie Potvin-Jutras, Ali Rezaei, Dalia Sabra, Christine Gagnon, Brittany Intzandt, Amélie Mainville-Berthiaume, Lindsay Wright, Mathieu Gayda, Josep Iglesies‐Grau, Anil Nigam, Louis Bherer, Claudine Joëlle Gauthier

This study examines the relationship between cardiorespiratory fitness and cerebral vascular and metabolic health in CAD patients and healthy individuals, finding fitness improves vascular function and partially preserves metabolic function in CAD.

bioRxiv · Aug 22, 2025 · PreprintBiophysics

Multivariate white matter microstructure alterations in older adults with coronary artery disease

Stefanie A Tremblay, Zacharie Potvin-Jutras, Dalia Sabra, Ali Rezaei, Safa Sanami, Christine Gagnon, Brittany Intzandt, Amélie Mainville-Berthiaume, Lindsay Wright, Ilana Ruth Leppert, Christine Lucas Tardif, Christopher J. Steele, Josep Iglesies‐Grau, Anil Nigam, Louis Bherer, Claudine Joëlle Gauthier

This study identifies white matter microstructural alterations in older adults with coronary artery disease using a multivariate approach and links them to cognitive performance.

Journal of Neuroscience · Aug 19, 2025Peer-reviewedNeuroscience

Sex-specific effects of intensity and dose of physical activity on BOLD-fMRI cerebrovascular reactivity and cerebral pulsatility

Zacharie Potvin-Jutras, Brittany Intzandt, Hânieh Mohammadi, Peiying Liu, J. Jean Chen, Claudine Joëlle Gauthier

This study examines how physical activity intensity and dose affect cerebrovascular reactivity and pulsatility differently in men and women, finding sex-specific patterns influenced by menopause.

Journal of Cerebral Blood Flow & Metabolism · Mar 13, 2025Peer-reviewedNeuroscience

The Impact of Coronary Artery Disease on Brain Vascular and Metabolic Health: Links to Cognitive Function

Safa Sanami, Stefanie A. Tremblay, Ali Rezaei, Zacharie Potvin-Jutras, Dalia Sabra, Brittany Intzandt, Christine Gagnon, Amélie Mainville-Berthiaume, Lindsay Wright, Mathieu Gayda, Josep Iglesies‐Grau, Anil Nigam, Louis Bherer, Claudine Joëlle Gauthier

This study investigates how coronary artery disease (CAD) affects cerebral vascular and metabolic health and links these changes to cognitive function, finding that reduced vascular reactivity and increased oxygen extraction fraction are associated with cognitive impairments.

Aging and Disease · Jan 1, 2025Peer-reviewedBiophysics

Sex moderates the relationship between aortic stiffness, cognition and cerebrovascular reactivity in healthy older adults

Dalia Sabra, Brittany Intzandt, Laurence Desjardins-Crépeau, Antoine Langeard, Christopher J. Steele, Frédérique Frouin, Richard D. Hoge, Louis Bherer, Claudine Joëlle Gauthier

This study examines how sex and hematocrit influence the relationship between aortic stiffness, cerebrovascular reactivity, and cognitive function in older adults.

PLoS ONE · Sep 28, 2021Peer-reviewedNeuroscience

Enhanced fitness relates to reduced cerebrovascular reactivity and perfusion in a sample of very healthy older adults

Brittany Intzandt, Dalia Sabra, Catherine Foster, Laurence Desjardins-Crépeau, Rick D. Hoge, Christopher J. Steele, Louis Bherer, Claudine Joëlle Gauthier

The paper examines the relationship between fitness, cerebral blood flow, and cerebrovascular reactivity in older adults, finding that higher fitness is associated with reduced cerebrovascular reactivity and altered hemodynamic responses.

bioRxiv · Oct 15, 2018 · PreprintNeuroscience