Author

Safa Sanami

Montreal Heart InstituteORCID 0000-0002-7451-5010Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 7 Assay:imaging· 6 Approach:statistical model· 6 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1

Frequent Co-Authors

Claudine Joëlle GauthieriD· 7 shared Zacharie Potvin-JutrasiD· 7 shared Ali RezaeiiD· 6 shared Anil NigamiD· 6 shared Christine GagnoniD· 6 shared Dalia Sabra· 6 shared Josep Iglesies‐GrauiD· 6 shared Lindsay WrightiD· 6 shared

Activity by Year

2025-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

7 shared papersNeuroscience

Claudine Joëlle GauthierORCID

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Regional distribution of white matter hyperintensity burden in coronary artery disease and links with coronary revascularization procedure

Zacharie Potvin-Jutras, Stefanie A Tremblay, Ali Rezaei, Safa Sanami, Dalia Sabra, Brittany Intzandt, Lindsay Wright, Christine Gagnon, Amélie Mainville-Berthiaume, Olivier Parent, Mahsa Dadar, Josep Iglesies‐Grau, Christopher J. Steele, Mathieu Gayda, Anil Nigam, , Claudine Joëlle Gauthier

This study examines regional white matter hyperintensity (WMH) burden in coronary artery disease (CAD) and finds that CAD is associated with higher WMH volumes, with CABG linked to greater superficial WMH burden than PCI.

bioRxiv · May 15, 2026 · PreprintNeuroscience

Greater cardiorespiratory fitness is associated with higher cerebral blood flow and lower oxygen extraction fraction in healthy older adults

Safa Sanami, Ali Rezaei, Stefanie A Tremblay, Zacharie Potvin-Jutras, Dalia Sabra, Brittany Intzandt, Christine Gagnon, Amélie Mainville-Berthiaume, Lindsay Wright, Mathieu Gayda, Josep Iglesies‐Grau, Anil Nigam, Louis Bherer, Claudine Joëlle Gauthier

This study finds that higher cardiorespiratory fitness in older adults is linked to increased cerebral blood flow and decreased oxygen extraction fraction.

Journal of Cerebral Blood Flow & Metabolism · Jan 16, 2026Peer-reviewedBiophysics

Coronary artery disease is linked with demyelination and iron deposition in white matter watershed areas

Ali Rezaei, Zacharie Potvin-Jutras, Stefanie A Tremblay, Safa Sanami, Dalia Sabra, Julia Huck, Christine Gagnon, Lindsay Wright, Ilana Ruth Leppert, Christine Lucas Tardif, Josep Iglesies‐Grau, Anil Nigam, Louis Bherer, Claudine Joëlle Gauthier

This study finds that coronary artery disease is associated with demyelination and increased iron deposition in white matter watershed regions, which correlate with cognitive decline.

Aging and Disease · Jan 1, 2026Peer-reviewedNeuroscience

Reduced cerebrovascular reactivity in youth with complex congenital heart defects

Claudine Joëlle Gauthier, Zacharie Potvin-Jutras, Safa Sanami, Kaitlyn Easson, Guillaume Gilbert, Christine Saint‐Martin, Marie Brossard‐Racine

This study finds persistent cerebrovascular reactivity deficits in youth with complex congenital heart defects compared to controls, with associations with cognitive performance.

bioRxiv · Nov 3, 2025 · PreprintNeuroscience

Preservation of cerebral vascular and metabolic health with greater cardiorespiratory fitness in coronary artery disease

Safa Sanami, Stefanie A Tremblay, Zacharie Potvin-Jutras, Ali Rezaei, Dalia Sabra, Christine Gagnon, Brittany Intzandt, Amélie Mainville-Berthiaume, Lindsay Wright, Mathieu Gayda, Josep Iglesies‐Grau, Anil Nigam, Louis Bherer, Claudine Joëlle Gauthier

This study examines the relationship between cardiorespiratory fitness and cerebral vascular and metabolic health in CAD patients and healthy individuals, finding fitness improves vascular function and partially preserves metabolic function in CAD.

bioRxiv · Aug 22, 2025 · PreprintBiophysics

Multivariate white matter microstructure alterations in older adults with coronary artery disease

Stefanie A Tremblay, Zacharie Potvin-Jutras, Dalia Sabra, Ali Rezaei, Safa Sanami, Christine Gagnon, Brittany Intzandt, Amélie Mainville-Berthiaume, Lindsay Wright, Ilana Ruth Leppert, Christine Lucas Tardif, Christopher J. Steele, Josep Iglesies‐Grau, Anil Nigam, Louis Bherer, Claudine Joëlle Gauthier

This study identifies white matter microstructural alterations in older adults with coronary artery disease using a multivariate approach and links them to cognitive performance.

Journal of Neuroscience · Aug 19, 2025Peer-reviewedNeuroscience

The Impact of Coronary Artery Disease on Brain Vascular and Metabolic Health: Links to Cognitive Function

Safa Sanami, Stefanie A. Tremblay, Ali Rezaei, Zacharie Potvin-Jutras, Dalia Sabra, Brittany Intzandt, Christine Gagnon, Amélie Mainville-Berthiaume, Lindsay Wright, Mathieu Gayda, Josep Iglesies‐Grau, Anil Nigam, Louis Bherer, Claudine Joëlle Gauthier

This study investigates how coronary artery disease (CAD) affects cerebral vascular and metabolic health and links these changes to cognitive function, finding that reduced vascular reactivity and increased oxygen extraction fraction are associated with cognitive impairments.

Aging and Disease · Jan 1, 2025Peer-reviewedBiophysics