Lisa Bast

MultiNeuronChat identifies cell type-specific communication perturbations in Alzheimer's disease using single-nucleus RNA-seq data and a database of synaptic molecules.

This study integrates genetic analysis with single nucleus RNA-seq to identify cell-type specific transcriptomic perturbations in schizophrenia, highlighting mitochondrial dysfunction and protein modification as key factors.

This study identifies an increase in asymmetric stem cell divisions with age as a key factor in the decline of neurogenesis in adult mice.