Cancer BiologybioRxivPreprint
Remodelling of chromatin architecture and super-enhancer landscape in lamin A/C depleted HGSOC
Shreyasi Dey Sarkar, Poulami Goswami, Amrutayani Panda…·Kaushik Sengupta
This study investigates the effects of lamin A/C depletion on chromatin organization in HGSOC, finding detethering of gene-poor chromatin, compartment switching, and rewiring of super-enhancers, leading to reduced proliferation.
DOI 10.64898/2026.09.07.749802