Author

Y S Zhang

Chinese University of Hong KongORCID 0000-0001-8515-3388Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Chenchen Xu· 1 shared Danyu Chen· 1 shared Felicia JiangiD· 1 shared Feng Liang· 1 shared Fengy Yang· 1 shared H T Wang· 1 shared Jia XuiD· 1 shared Jiuyang Tang· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Chenchen Xu

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 7, 2026

Structure-aware protein function prediction at isoform resolution

Felicia Jiang, Runhao Zhao, Feng Liang…·Xin Wang

This study develops a framework for predicting protein function and domain annotation at isoform resolution using structural and sequence data, showing strong performance in benchmark tests and capturing domain changes across isoforms.

DOI 10.64898/2026.04.24.720502

humanprotein structure

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BioinformaticsbioRxivPreprintMay 15, 2026

TDP-43 regulates chromatin looping and gene transcription through binding and stabilizing DNA G-quadruplex structures

Fengy Yang, Suyang Zhang, Xiaofan Guo…·H T Wang

This study shows TDP-43 binds and stabilizes DNA G-quadruplexes, enhancing chromatin looping and gene expression in K562 and HepG2 cells.

DOI 10.64898/2026.05.13.724493

humanChIP-seq

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