Author

Xiaofan Guo

Chinese University of Hong KongORCID 0000-0002-7220-5094Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:Hi-C· 1

Frequent Co-Authors

Suyang ZhangiD· 2 shared Xiaona CheniD· 2 shared Yulong QiaoiD· 2 shared Chun Kit KwokiD· 1 shared Feng YangiD· 1 shared Fengy Yang· 1 shared H T Wang· 1 shared Hao SuniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBioinformatics

Suyang ZhangORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintMay 15, 2026

TDP-43 regulates chromatin looping and gene transcription through binding and stabilizing DNA G-quadruplex structures

Fengy Yang, Suyang Zhang, Xiaofan Guo…·H T Wang

This study shows TDP-43 binds and stabilizes DNA G-quadruplexes, enhancing chromatin looping and gene expression in K562 and HepG2 cells.

DOI 10.64898/2026.05.13.724493

Molecular BiologyGenome biologyPeer-reviewedSep 5, 2025

DNA G-quadruplex Profiling Reveals Functional and Mechanistic Role of G-quadruplexes in Skeletal Muscle Stem Cells

Xiaona Chen, Feng Yang, Suyang Zhang…·Huating Wang

This study maps G-quadruplexes in skeletal muscle stem cells and shows their role in promoting activation and regeneration through chromatin looping and transcription factor binding.

4 citations

mouseDNA methylation