Author

Liying Zhang

Center for Life SciencesORCID 0000-0001-8520-267XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Beibei LiuiD· 1 shared Haoxiang LiiD· 1 shared Huasong AiiD· 1 shared Jialin Bian· 1 shared Jiao HuaiD· 1 shared Jiawei LiangiD· 1 shared Jing QiiD· 1 shared Jiqing ZhengiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Beibei LiuORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJun 8, 2025

A Cryptic Interfacial Pocket Uncovered in Full CRL4CRBN-IKZF3 Ubiquitylation Complex Enhances IMiD Efficacy

Zhiheng Deng, Huasong Ai, Qiang Shi…·Lei Liu

The paper determines cryo-EM structures of IMiDs in full CRL4CRBN complexes, revealing a cryptic interfacial pocket that enhances IMiD efficacy and neosubstrate specificity.

2 citations

cryo-EMexperimental assay

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BioinformaticsInternational Journal of Environmental Research and Public HealthPeer-reviewedJan 2, 2021

The scRNA-seq expression profiling of the receptor ACE2 and the cellular protease TMPRSS2 reveals human organs susceptible to COVID-19 infection

Jing Qi, Yang Zhou, Jiao Hua…·Shuilin Jin

The paper uses scRNA-seq data to identify organs with high ACE2 and TMPRSS2 expression, revealing susceptibility to COVID-19 infection across multiple systems.

135 citationstop 2%

humanscRNA-seq

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