Alexander A. Sousa

The paper introduces SCRIBBLE, a lineage tracing tool that enables high-resolution, multigenerational lineage tracking in embryonic mouse retina.

This study demonstrates in vivo gene therapy for hemoglobinopathies using EPOR editing to enhance the expansion of gene-corrected erythroid cells without drug selection.

OptiPrime predicts prime editing outcomes with high accuracy, enabling efficient therapeutic applications in human and mouse cells.

This paper introduces a proteogenomic framework combining genetic perturbations and proteomics to map phospho-signaling pathways in primary human T cells, validated with inflammatory stimuli.