Christian Michel Beusch

This study shows that HIV-1 capsid binding remodels PQBP1 conformation to enable cGAS recruitment, linking capsid recognition to innate immune activation.

This study shows that IL-6 restricts pre-thymic T cell lineage commitment in SIV-infected rhesus macaques, contributing to loss of viral control.

This paper introduces a proteogenomic framework combining genetic perturbations and proteomics to map phospho-signaling pathways in primary human T cells, validated with inflammatory stimuli.

This study introduces SC-pSILAC, a method to measure protein abundance and turnover in single cells, revealing differentiation-specific dynamics and cell-type markers in human iPSCs.

This study profiles longitudinal proteomic and phosphoproteomic changes in CD8 T cells during acute and chronic infections, identifying exhaustion-associated proteins and phosphosites with potential therapeutic relevance.

This study shows that ultralight Caenorhabditis elegans, grown on isotopically depleted bacteria, have shorter lifespans despite faster growth and maturation.