Cell BiologybioRxivPreprint
Combination of enhanced gene activation and cell death causes lethal inflammatory pulmonary fibrosis
Julia Saggau, Christine Kiefer, Debora Bonasera…·Henning Walczak
The paper shows that enhanced gene activation in specific LUBAC mutants leads to cell death and lethal lung fibrosis, revealing gene activation as a root cause of inflammatory disease.
DOI 10.64898/2026.09.03.749194