Sophie Pantalacci

Patterns of molecular conservation along tooth development are only partly shaped by evolutionary pressures on tooth

The paper examines molecular conservation patterns during molar development in mice and hamsters, finding that conservation varies with developmental stage and is influenced by both intrinsic and extrinsic evolutionary pressures.

Single-cell transcriptomics uncover conserved molecular mechanisms and functional diversification in multilayered epithelia

The paper identifies a conserved p63-Notch axis in multilayered epithelia and shows how context-specific modules generate functional diversity.

Pleiotropy accelerates tooth phenotypic and genomic evolution - An in silico study under the lens of development

This paper uses in silico evolution to study how pleiotropy affects genetic and phenotypic evolution, finding that it accelerates genetic divergence and promotes fitness improvements.

Inverse hourglass pattern of conservation in rodent molar development.

The paper identifies an inverse hourglass pattern of conservation in rodent molar development, showing greater conservation at early and late stages than intermediate ones.

Convergent transcriptomic and genomic adaptation in xeric rodents

This study identifies convergent transcriptomic and genomic changes in xeric rodents, showing increased convergence with adaptation age and species relatedness.

Modeling Edar expression reveals the hidden dynamics of tooth signaling center patterning

The paper models Edar expression dynamics to reveal hidden patterning processes in tooth signaling centers, showing a two-step activation and erasure mechanism.