ImmunologybioRxivPreprint
Lactate promotes IL-8 secretion in human alveolar macrophages through GPR132 and lipid metabolic reprogramming
DOI 10.64898/2026.01.27.701994
Author
University of BirminghamORCID 0000-0001-8609-9539Unclaimed ORCID profile · follow to get notified of new preprints
2 papers
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Chloe Lockwood, Kalbinder K Daley, John D. O’Neil…·Andrew R. Clark
This study shows dexamethasone inhibits LPS-induced HIF-1α activation in macrophages through a glucocorticoid-sensitive mechanism, independent of the DUSP1-p38-TTP-HIF-1α pathway.