Author

Chloe Lockwood

University of BirminghamORCID 0009-0001-5100-4576Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Andrew R. ClarkiD· 1 shared John D. O’NeiliD· 1 shared Kalbinder K DaleyiD· 1 shared Katherine J HeighesiD· 1 shared Sally A. ClaytoniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

Andrew R. ClarkORCID

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintSep 19, 2025

Dexamethasone inhibits the LPS-induced activation of hypoxia-inducible factor 1 alpha (HIF-1α) in macrophages independently of the DUSP1-p38-TTP-HIF-1α regulatory axis.

Chloe Lockwood, Kalbinder K Daley, John D. O’Neil…·Andrew R. Clark

This study shows dexamethasone inhibits LPS-induced HIF-1α activation in macrophages through a glucocorticoid-sensitive mechanism, independent of the DUSP1-p38-TTP-HIF-1α pathway.

1 citation

mouseexperimental assay

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