Bruno Gegenhuber

The paper shows that somatosensory neuron repertoires in mammals diversify through changes to conserved neuron types, enabling adaptation to different habitats and body forms.

This study identifies area postrema neurons as mediators of IL-6 function in cancer-associated cachexia, showing that targeting these neurons can prevent cachexia and prolong lifespan in mice.

The paper shows that estrogen enhances activity in melanocortin neurons, reducing sedentary behavior and linking estrogen signaling to metabolic regulation.

This study identifies ER-regulated genes in a sexually dimorphic neural circuit, showing ER induces a neurodevelopmental gene program and interacts with Nfix to regulate male-biased gene expression.