ImmunologyCell chemical biologyPeer-reviewed
Covalent Targeting of Splicing in T Cells.
Kevin A. Scott, Hiroyuki Kojima, Nathalie Ropek…·Ekaterina V. Vinogradova
This study develops chemical probes to target splicing factors in T cells, showing state-dependent loss of ITK via SF3B1 and demonstrating covalent ligandability of splicing regulators.
16 citations