Author

Sakshi Garg

Merck Healthcare KGaA, Darmstadt (Germany)ORCID 0000-0001-8662-5949Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Sakshi Garg1 paper · Brigham and Women's Hospital

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Assay:imaging· 3 Research Focus:benchmarking· 2 Approach:experimental assay· 2 Research Focus:batch correction / integration· 1 Approach:benchmark study· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Amy B. GoodaleiD· 3 shared Anne Elizabeth CarpenteriD· 3 shared Beth A. CiminiiD· 3 shared Briana Fritchman· 3 shared Desiree Hernandez· 3 shared Lisa MilleriD· 3 shared Maria Kost‐AlimovaiD· 3 shared Shantanu SinghiD· 3 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBioinformatics

Amy B. GoodaleORCID

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3 papers

Recent·Most cited

BioinformaticsNature MethodsPeer-reviewedApr 9, 2024

Three million images and morphological profiles of cells treated with matched chemical and genetic perturbations

Srinivas Niranj Chandrasekaran, Beth A. Cimini, Amy B. Goodale…·Anne Elizabeth Carpenter

The paper introduces a dataset of cell morphology images treated with matched chemical and genetic perturbations and evaluates methods for identifying perturbation similarities.

160 citationstop 1%

imagingbenchmark study

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BioinformaticsNature ProtocolsPeer-reviewedJun 21, 2023

Optimizing the Cell Painting assay for image-based profiling

Beth A. Cimini, Srinivas Niranj Chandrasekaran, Maria Kost‐Alimova…·Anne Elizabeth Carpenter

The paper updates the Cell Painting assay protocol to improve morphological profiling, finding that simplified steps and reduced stain concentrations maintain robust outputs.

177 citationstop 1%

imagingexperimental assay

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BioinformaticsbioRxivPreprintMar 23, 2023

✦ In-depth digest

JUMP Cell Painting chemical dataset: Morphological map of 115,796 compounds in human cells

Srinivas Niranj Chandrasekaran, Jeanelle Ackerman, Eric Alix…·Anne Elizabeth Carpenter

Cell Painting images and profiles for 115,796 compounds in U2OS cells from 12 laboratories; 15.2% of analyzed compounds are phenotypically active, and cross-laboratory replicates cut reference-compound activity by 34%.

98 citations

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