Author

Ashrafali Mohamed Ismail

Massachusetts Eye and Ear InfirmaryORCID 0000-0001-8694-7235Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Emanuel Garcia· 2 shared James ChodoshiD· 2 shared Jaya RajaiyaiD· 2 shared Amrita SahaiD· 1 shared Amrita Saha· 1 shared Dominic K. LUNDQUIST· 1 shared Judy L. CannoniD· 1 shared Kimberly A. MorrisseyiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

Emanuel Garcia

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2 papers

Recent·Most cited

MicrobiologyPLoS PathogensPeer-reviewedMay 14, 2025

Virus and Cell Specific HMGB1 Secretion and Subepithelial Infiltrate Formation in Adenovirus Keratitis

Amrita Saha, Mohammad Mirazul Islam, Rahul Kumar…·Jaya Rajaiya

This study identifies HAdV-D-specific mechanisms of HMGB1 secretion and subepithelial infiltrate formation in EKC by infected corneal epithelial cells.

2 citations

humanproteomics

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Cell BiologybioRxivPreprintApr 23, 2025

OCT4 Negatively Regulates the Transcriptional Programming of the Early Region 3 Immune Evasion Genes of Human Adenovirus

Ashrafali Mohamed Ismail, Amrita Saha, Kimberly A. Morrissey…·Jaya Rajaiya

This study identifies OCT4's role in repressing adenovirus E3 gene expression through binding to the ITR, affecting immune evasion and viral replication.

1 citation

humanChIP-seq

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