BiochemistrybioRxivPreprint
Neuroblastoma-associated ALK variants have distinct cellular and biochemical activities
Anna Magdalena Wulf, Stuart Lutimba, Dylan Cameron…·Karen J. Liu
This study investigates the functional effects of ALK variants in neural crest cells, showing that ALKF1174L increases migration and cytoskeletal protrusions through GSK3 binding.
DOI 10.1101/2025.09.25.677354