Leone Rossetti

Single cell migration along and against confined haptotactic gradients

This study shows cells exhibit complex migration patterns along haptotactic gradients, including oscillations and directed movement, and develops a biophysical model to explain these behaviors.

Neuroblastoma-associated ALK variants have distinct cellular and biochemical activities

This study investigates the functional effects of ALK variants in neural crest cells, showing that ALKF1174L increases migration and cytoskeletal protrusions through GSK3 binding.

Parametric modeling of mechanical effects on circadian oscillators

This paper extends a biochemical model of circadian rhythms to include mechanical effects, showing that mechanical signals must be within an optimal range for oscillations to occur.