Author

Haoran Wang

Chinese Academy of SciencesORCID 0000-0001-8733-9266Unclaimed ORCID profile · follow to get notified of new preprints

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Haoran Wang1 paper · BGI Research

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

Chen FangiD· 1 shared Houxin He· 1 shared Huanhuan WuiD· 1 shared Jiaxin HuiD· 1 shared Limeng Tian· 1 shared Wentao CuiiD· 1 shared Xiaoning QiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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1 shared paperBioinformatics

Chen FangORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintSep 24, 2026

A closed-loop language-model agent for target-specific multi-objective hit-to-lead optimization

Wentao Cui, Limeng Tian, Xiaoning Qi…·Jiaxin Hu

This paper develops a language-model agent for hit-to-lead optimization that outperforms existing methods on four kinase targets in a computational benchmark.

DOI 10.64898/2026.09.19.752921

deep learningstatistical model

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