Author

Limeng Tian

Tsinghua University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:perturbation response prediction· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Jiaxin HuiD· 2 shared Xiaoning QiiD· 2 shared Chen FangiD· 1 shared Haoran WangiD· 1 shared Houxin He· 1 shared Huanhuan WuiD· 1 shared Jie Yan· 1 shared Nian Liu· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioinformatics

Jiaxin HuORCID

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2 papers

Recent·Most cited

Cause-excluded Effect Evaluation: a framework for the faithful assessment of genetic perturbation target identification

Jiaxin Hu, Xiaoning Qi, Limeng Tian, Jie Yan, Nian Liu, Xin Li

The paper introduces CEE, a framework to assess genetic perturbation target identification by eliminating evaluation artefacts, and finds simple methods outperform complex models.

bioRxiv · Oct 11, 2026 · PreprintBioinformatics

A closed-loop language-model agent for target-specific multi-objective hit-to-lead optimization

Wentao Cui, Limeng Tian, Xiaoning Qi, Haoran Wang, Huanhuan Wu, Houxin He, Chen Fang, Jiaxin Hu

This paper develops a language-model agent for hit-to-lead optimization that outperforms existing methods on four kinase targets in a computational benchmark.

bioRxiv · Sep 24, 2026 · PreprintBioinformatics