Author

Shangze Xu

Newcastle UniversityORCID 0000-0001-8736-2298Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Agnieszka K. BronowskaiD· 2 shared Amelia StennettiD· 1 shared Aniketh BishnuiD· 1 shared Bernardo S. FrankliniD· 1 shared Chloe M. McKeeiD· 1 shared Conchita Fraguas BringasiD· 1 shared Congxin Sun· 1 shared Damien BerthelootiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Agnieszka K. BronowskaORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMay 21, 2026

AMPK senses cellular levels of nicotinamide adenine dinucleotide

Niall Wilson, Yoana Rabanal‐Ruiz, Aniketh Bishnu…·Viktor I. Korolchuk

This study shows that AMPK senses NAD levels, with NAD binding to the gamma subunit and modulating AMPK activity, which affects metabolic pathways like mTORC1 and autophagy.

1 citation

humanstatistical model

ImmunologybioRxivPreprintSep 29, 2025

NLRP3 is a thermosensor that is negatively regulated by high temperature

Wei Wang, Damien Bertheloot, Junya Zhang…·Rebecca C. Coll

This study shows high temperatures inhibit NLRP3 inflammasome activation, identifying NLRP3 as a thermosensor and revealing a temperature-sensitive conformational change in its C-terminal domain.

2 citations

mouseexperimental assay