NeurosciencebioRxivPreprint
Neuronal activity regulates Matrin 3 levels and function in a calcium-dependent manner through calpain cleavage and calmodulin binding
Ahmed Mujtaba Malik, Josephine J. Wu, Christie A. Gillies…·Sami J. Barmada
This study shows that neuronal activity regulates MATR3 levels and function through calpain cleavage and Ca2+/calmodulin binding, linking these processes to ALS pathology.
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