Identification and characterization of inflammatory LILR and fibrotic SPP1 macrophages in chronic lung allograft dysfunction
Allen Duong, Sajad Moshkelgosha, Aaron Wong, Ankita Burman, Ke Fan Bei, Rayoun Ramendra, Tsukasa Ishiwata, Boris Hinz, Sonya A. MacParland, Mingyao Liu, S. Juvet, Tereza Martinu
This study identifies two distinct macrophage populations in chronic lung allograft dysfunction using single-cell RNA sequencing and characterizes their functional roles in inflammation and fibrosis.
bioRxiv · Sep 9, 2026 · PreprintImmunology