Tereza Martinu

This study identifies two distinct macrophage populations in chronic lung allograft dysfunction using single-cell RNA sequencing and characterizes their functional roles in inflammation and fibrosis.

The paper identifies distinct transcriptomic signatures in chronic lung allograft dysfunction phenotypes using bulk RNA sequencing and non-negative matrix factorization.

The paper identifies CD4+CD57+PD1+ T cells in lung transplant recipients that predict allograft dysfunction and are associated with fibrosis in both human and mouse models.

The paper uses proteomics to identify ECM injury in kidney allografts with early AMR, finding decreased ECM proteins and increased LGALS1 and GSTO1 in affected tissues.