Author

Ashraf Brik

Technion – Israel Institute of TechnologyORCID 0000-0001-8745-2250Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:proteomics· 1

Frequent Co-Authors

Ajay R. WaghiD· 1 shared Amir OrianiD· 1 shared Avital Oknin-VaismaniD· 1 shared Deepanjan PandaiD· 1 shared Eden Filimonov· 1 shared Eliya Bitman-LotaniD· 1 shared Fabian GlaseriD· 1 shared Ghazal KheshaibouniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Ajay R. WaghORCID

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2 papers

Recent·Most cited

Cancer BiologyOncogenePeer-reviewedJun 5, 2026

Eliminating Aggressive Cancers via PROTAC-like Inducers of Ferroptosis

Avital Oknin-Vaisman, Deepanjan Panda, Rostislav Novak…·Amir Orian

This paper develops R4VPs, PROTAC-like compounds that induce ferroptosis in aggressive cancers while sparing normal cells, showing efficacy against therapy-resistant melanoma and sarcomas.

DOI 10.1038/s41388-026-03829-2

humanexperimental assay

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BiochemistrybioRxivPreprintAug 13, 2025

USP15: the fourth Proteasome-associated DUB

Shahar Levi, Fabian Glaser, Ajay R. Wagh…·Indrajit Sahu

The paper identifies USP15 as a fourth proteasome-associated DUB, showing it binds transiently to proteasomes and selectively disassembles short polyubiquitin chains.

DOI 10.1101/2025.08.13.670075

humanproteomics

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