Michael C. Anderson

The paper maps the spatial relationships between NMDA receptor subunits and synaptic proteins, revealing a nanotopography that promotes NMDAR activation and synaptic transmission tuning.

This paper uses a modified CRISPR method to replace the entire coding sequence of LRRTM2 in rat neurons, revealing its synaptic distribution and interactions with AMPARs.

This paper develops a high-throughput optical method to analyze glutamatergic synapse function in cultured rat neurons, revealing functional heterogeneity across synaptic boutons.

The paper develops a computational model of the Drosophila larval locomotor system to show how inhibitory circuit motifs generate motor program diversity and variability.

This study uses super-resolution microscopy to show that SAP102 forms distinct nanoclusters at synapses, differing from PSD-95 in size, density, and co-localization patterns.

This study shows that loss of NMDARs leads to changes in pre- and postsynaptic nanocluster organization, affecting synaptic function differently than pharmacological antagonism.

The paper identifies a direct trigeminal ganglion-to-parabrachial connection that processes dura inputs, suggesting a role in migraine pathogenesis.