Inflammatory stress-mediated chromatin changes underlie dysfunction in endothelial cells.
Haibo Liu, Amada D. Caliz, Heather Learnard, Milka Koupenova, John F. Keaney, Shashi Kant, Lihua Julie Zhu, Anastassiia Vertii
The paper investigates chromatin changes in human endothelial cells under inflammatory stress using ATAC-seq and RNA-seq, finding correlations between chromatin accessibility and gene expression related to endothelial dysfunction.
bioRxiv · Oct 11, 2023 · PreprintGenomics