Haibo Liu

OTTR-CLASH: improved biochemical and bioinformatic identification of Argonaute 2-mediated microRNA-target RNA interactions

The paper introduces OTTR-CLASH, a method that improves the detection of miRNA-target interactions by using a modified RT and enhanced bioinformatics pipeline.

Inflammatory stress-mediated chromatin changes underlie dysfunction in endothelial cells.

The paper investigates chromatin changes in human endothelial cells under inflammatory stress using ATAC-seq and RNA-seq, finding correlations between chromatin accessibility and gene expression related to endothelial dysfunction.

Stromal Hippo-YAP signaling in stem cell niche controls intestinal homeostasis

This study identifies the role of stromal Hippo-YAP signaling in maintaining intestinal homeostasis by regulating stem cell niche function and epithelial regeneration.

dagLogo: an R/Bioconductor package for identifying and visualizing differential amino acid group usage in proteomics data

The paper introduces dagLogo, an R/Bioconductor package for identifying and visualizing differential amino acid group usage in proteomics data, showing improved performance in detecting conserved sequence patterns.

Two Contrasting Classes of Nucleolus-Associated Domains in Mouse Fibroblast Heterochromatin

The paper identifies two distinct classes of Nucleolus-Associated Domains (NADs) in mouse fibroblasts using deep sequencing and a new tool, showing differences in chromatin features and gene expression.