Jia Yu Koh

The paper analyzes gut metagenomes of Asian octogenarians to identify age-related microbial shifts and their associations with aging phenotypes.

This study presents whole-genome sequencing data from 4,810 Singaporeans across three ethnic groups, revealing genetic structure, admixture, and improved imputation for Asian and Oceanian populations.

This paper introduces a hybrid metagenomic assembler that improves assembly quality and enables high-resolution analysis of resistance determinants and mobile elements in the human gut microbiome.

ConsensusDriver improves driver alteration prediction by combining multiple methods, increasing sensitivity by 20% across cancer types and individual patients.

The paper identifies 25 genetic loci associated with subcortical brain structure volumes in over 40,000 individuals, revealing novel biology and potential drug targets.