Author

Serkan Sayin

University of Massachusetts Chan Medical SchoolORCID 0000-0001-8776-2240Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Organism:E. coli· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Amir MitchelliD· 2 shared Brittany RoseneriD· 2 shared Albertha J.M. WalhoutiD· 1 shared Andrew MugleriD· 1 shared Bao HoiD· 1 shared Carmen G LiiD· 1 shared Doyle V. WardiD· 1 shared Michael A. BrehmiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersSystems Biology

Amir MitchellORCID

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2 papers

Recent·Most cited

Systems BiologyMolecular Systems BiologyPeer-reviewedDec 15, 2025

Bacterial population dynamics during colonization of solid tumors

Serkan Sayin, Motasem ElGamel, Brittany Rosener…·Amir Mitchell

This study investigates bacterial population dynamics in murine tumors, revealing nonuniform growth and a scale-free distribution of bacterial clone sizes.

3 citations

mousestatistical model

𝕏 PostBluesky

Systems BiologyeLifePeer-reviewedJan 30, 2023

Evolved bacterial resistance to the chemotherapy gemcitabine modulates its efficacy

Serkan Sayin, Brittany Rosener, Carmen G Li…·Amir Mitchell

The paper shows that evolved bacterial resistance to gemcitabine can either reduce or increase its efficacy in the local environment by altering drug breakdown.

30 citationstop 4%

E. coliexperimental assay

𝕏 PostBluesky