Author

Sepideh Afshar

Harvard UniversityORCID 0000-0001-8778-4386Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:imaging· 3 Organism:non-human primate· 3 Organism:rat· 3 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

Anna‐Liisa BrownelliD· 3 shared Gengyang YuaniD· 3 shared Georges El FakhriiD· 3 shared Maëva DhaynautiD· 3 shared Marc D. NormandiniD· 3 shared Nicolas J. GuehliD· 3 shared Sung‐Hyun MooniD· 3 shared Dalena HuynhiD· 2 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Anna‐Liisa BrownellORCID

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3 papers

Recent·Most cited

NeuroscienceJournal of Cerebral Blood Flow & MetabolismPeer-reviewedSep 28, 2022

PET imaging studies to investigate functional expression of mGluR2 using mG2P001

Gengyang Yuan, Maëva Dhaynaut, Nicolas J. Guehl…·Marc D. Normandin

The paper investigates the functional expression of mGluR2 using PET imaging with [11C]mG2P001, showing increased accumulation with pretreatment and validating its use as a biomarker.

6 citations

ratnon-human primate

𝕏 PostBluesky

NeuroscienceJournal of Medicinal ChemistryPeer-reviewedJul 8, 2022

Design, synthesis, and characterization of mG2P026 as a high contrast PET imaging ligand for metabotropic glutamate receptor 2

Gengyang Yuan, Maëva Dhaynaut, Nicolas J. Guehl…·Anna‐Liisa Brownell

The paper describes the synthesis and characterization of [18F]mG2P026 as a PET ligand for mGluR2, showing improved brain permeability and binding compared to existing compounds.

8 citations

ratnon-human primate

𝕏 PostBluesky

NeuroscienceJournal of Medicinal ChemistryPeer-reviewedJan 28, 2022

Synthesis and characterization of 5-(2-fluoro-4-pyridine-7-carboxamide as a PET imaging ligand for metabotropic glutamate receptor 2

Gengyang Yuan, Maëva Dhaynaut, Yu Lan…·Anna‐Liisa Brownell

The paper develops and characterizes [11C]13, a PET ligand for mGluR2, showing its brain distribution and response to mGluR2 NAMs in rats and nonhuman primates.

5 citations

ratnon-human primate

𝕏 PostBluesky