Sandra A. Brown

The paper examines how maturation of corticostriatal circuits during adolescence and early adulthood relates to alcohol use initiation and escalation.

This study examines how binge drinking affects gray matter volume decline in adolescents over time, finding stronger effects in younger individuals and suggesting potential for recovery with temporally proximal drinking.

This paper investigates heterogeneous genetic effects on smoking behaviors using UK Biobank data, finding evidence of sex- and psychiatric disorder-specific genetic associations and improved polygenic risk score prediction with sex-specific effects.

This study conducts a genome-wide association meta-analysis of childhood aggression across multiple raters, instruments, and ages, identifying genetic correlations with various traits but no genome-wide significant SNPs.

This study uses a data-driven method to show that alcohol use in adolescents affects cortical thinning differently across age groups.

The paper compares genome-wide data from opioid use and dependence cases to identify genetic associations and differences between exposure and dependence.

The paper imputes four VNTR polymorphisms and one modifying SNP into 486,551 UK Biobank individuals, enabling rigorous testing of their association with psychiatric phenotypes.