Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits.
Emma C. Johnson, Dongbing Lai, Jared V. Balbona, Alex P. Miller, Alexander Samir Hatoum, Joseph D. Deak, Mariela V. Jennings, David A. A. Baranger, Marco Galimberti, Kittipong Sanichwankul, Thorgeir Elís Thorgeirsson, Sarah M. C. Colbert, Keyrun Adhikari, Anna R. Docherty, Louisa J Degenhardt, , Arpana Agrawal A
This study performs a multi-ancestral GWAS of DSM-defined nicotine dependence, finding genetic correlations with other substance use disorders and health traits, and identifying a strong general addiction liability factor.
Psychological Medicine · Jan 1, 2025Peer-reviewedGenetic & Genomic Medicine