GenomicsbioRxivPreprint
In vivo BMAL1 occupancy mapping using MACS-Calling Cards reveals disease-associated retargeting in Cln3Δex7/8 astrocytes
India Reiss, Jonathan D. Cooper, Erik S. Musiek, Robi David Mitra
The paper introduces MACS-Calling Cards to map astrocyte-specific TF occupancy in vivo and finds BMAL1 binding is redistributed in a neurodegenerative disease model due to loss of cooperative TF interactions.