Author

Christoph A. Merten

European Molecular Biology LaboratoryORCID 0000-0001-8790-4659Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Julio Sáez-RodrígueziD· 2 shared Bence SzalaiiD· 1 shared Federica EduatiiD· 1 shared Jessica WappleriD· 1 shared Jonathan J. M. LandryiD· 1 shared Lukas MathuriD· 1 shared Martine BallingeriD· 1 shared Mathew J. GarnettiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersSystems Biology

Julio Sáez-RodríguezORCID

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2 papers

Recent·Most cited

Systems BiologyNature CommunicationsPeer-reviewedAug 1, 2022

Combi-Seq: Multiplexed transcriptome-based profiling of drug combinations using 1deterministic barcoding in single-cell droplets

Lukas Mathur, Bence Szalai, N. H. Du…·Christoph A. Merten

The paper develops a method to screen drug combinations using single-cell transcriptome analysis, identifying synergistic and antagonistic pairs in K562 cells.

29 citations

humanbulk RNA-seq

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Systems BiologyMolecular Systems BiologyPeer-reviewedFeb 1, 2020

Patient-specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies

Federica Eduati, Patricia Jaaks, Jessica Wappler…·Julio Sáez-Rodríguez

The paper develops patient-specific signaling pathway models using microfluidic screenings and logic-based modeling to predict personalized cancer therapies.

74 citationstop 4%

humanstatistical model

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