BiochemistryAngewandte Chemie International EditionPeer-reviewed
Peptidic tryptophan halogenation by a promiscuous flavin-dependent enzyme
Andrew J. Rice, Mayuresh G. Gadgil, Paola Bisignano…·Douglas A. Mitchell
The paper characterizes ChlH, a flavin-dependent halogenase that halogenates internal and terminal tryptophan residues in diverse peptides and proteins, showing broad substrate promiscuity.
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