Paola Bisignano

The paper characterizes ChlH, a flavin-dependent halogenase that halogenates internal and terminal tryptophan residues in diverse peptides and proteins, showing broad substrate promiscuity.

This study reveals how lipid competition modulates drug affinity in ABC exporters through structural and simulation analyses of BmrCD.

This study investigates how zafirlukast and pranlukast inhibit LRRC8 channels by identifying their binding sites and showing they destabilize the channel pore.