Author

Valentina Carlini

Heidelberg UniversityORCID 0000-0001-8797-8527Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ChIP-seq· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Cristina PolicarpiiD· 2 shared Jamie A. HackettiD· 2 shared Marzia MunafòiD· 1 shared Stylianos TsagkrisiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersSynthetic Biology

Cristina PolicarpiORCID

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2 papers

Recent·Most cited

Synthetic BiologyNature GeneticsPeer-reviewedMay 9, 2024

Systematic Epigenome Editing Captures the Context-dependent Instructive Function of Chromatin Modifications

Cristina Policarpi, Marzia Munafò, Stylianos Tsagkris…·Jamie A. Hackett

This study uses epigenome editing to systematically analyze how chromatin modifications influence transcription, revealing context-dependent regulatory mechanisms.

151 citationstop 1%

experimental assay

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GeneticsThe EMBO JournalPeer-reviewedFeb 24, 2022

Epigenetic Inheritance is Gated by Naive Pluripotency and Dppa2

Valentina Carlini, Cristina Policarpi, Jamie A. Hackett

The paper investigates how epigenetic inheritance is restricted in mammals by showing that naive pluripotency erases heterochromatin domains, but lineage specification allows probabilistic inheritance under favorable conditions.

21 citations

mouseChIP-seq

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